Autosomal Dominant
Autosomal Dominant
Autosomal Dominant
Autosomal Dominant
Autosomal Dominant
Autosomal Dominant
Autosomal Dominant
Autosomal Dominant
Autosomal Dominant
Autosomal Dominant
Autosomal Dominant
Autosomal Dominant
Autosomal Dominant
Autosomal Dominant
X Linked
X Linked
X Linked
X Linked
X Linked
X Linked
X Linked
X Linked
X Linked
X Linked
Autosomal Recessive
Autosomal Recessive
Autosomal Recessive
Autosomal Recessive
Autosomal Recessive
Autosomal Recessive
Autosomal Recessive
Autosomal Recessive
Autosomal Recessive
Autosomal Recessive
Autosomal Recessive
Autosomal Recessive
DR2, 3.
B8, DR3.
B8, DR3, 4.
DR3, 4.
DR3, 5.
DQ2, 8.
B8.
B27.
DR2.
DR3.
DR4.
DR5.
Receptor tyrosine kinase.
Lung adenocarcinoma.
Oncogene
Tyrosine kinase.
CML, ALL.
Oncogene
Antiapoptotic molecule (inhibits apoptosis).
Follicular and diffuse large B cell lymphomas.
Oncogene
Serine/threonine kinase.
Melanoma, non-Hodgkin lymphoma, papillary thyroid carcinoma.
Oncogene
Cytokine receptor
Gastrointestinal stromal tumor (GIST).
Oncogene
Transcription factor
Burkitt lymphoma.
Oncogene
Receptor tyrosine kinase
Breast and gastric carcinomas.
Oncogene
Tyrosine kinase
Chronic myeloproliferative disorders.
Oncogene
GTPase
Colon cancer, lung cancer, pancreatic cancer.
Oncogene
Transcription factor
Lung tumor.
Oncogene
Transcription factor
Neuroblastoma.
Oncogene
Receptor tyrosine kinase
MEN 2A and 2B, medullary thyroid cancer.
Oncogene
Negative regulator of β-catenin/WNT pathway
Colorectal cancer (associated with FAP).
Tumor suppressor
DNA repair protein
Breast, ovarian, and pancreatic cancer.
Tumor suppressor
p16, blocks G1 to S phase
Melanoma, pancreatic cancer.
Tumor suppressor
Deleted in Colon Cancer
Colon cancer.
Tumor suppressor
Deleted in Pancreatic Cancer
Pancreatic cancer.
Tumor suppressor
Menin
MEN 1.
Tumor suppressor
Neurofbromin (Ras GTPase activating protein)
Neurofibromatosis type 1.
Tumor suppressor
Merlin (schwannomin) protein
Neurofibromatosis type 2.
Tumor suppressor
Tyrosine phosphatase of PIP3 (eg, protein kinase B [AKT] activation)
Breast cancer, prostate cancer, endometrial cancer.
Tumor suppressor
Inhibits E2F; blocks G1 p S phase
Retinoblastoma, osteosarcoma.
Tumor suppressor
p53, activates p21, blocks G1 to S phase
Most human cancers, Li-Fraumeni syndrome.
Tumor suppressor
Hamartin protein
Tuberous sclerosis.
Tumor suppressor
Tuberin protein
Tuberous sclerosis.
Tumor suppressor
Inhibits hypoxia inducible factor 1a
von Hippel-Lindau disease.
Tumor suppressor
Transcription factor that regulates urogenital development
Wilms tumor nephroblastoma.
Tumor suppressor
SBLA cancer syndrome: Sarcoma, Breast, Leukemia, Adrenal gland..